If you are using file based EHCache in Coldfusion you will run into serious troubles with ColdFusion 10 Updater 14 and your application goes down. You can find this case in bugtracker #3858286: CacheManager has been shut down error with Update 14. These updater contains an upgrade of EHCache library from version 2.5.1 to 2.6.6 to fix the bug #3339491: Upgrading Ehcache causes silent failure and unexpected behavior. You may have also seen that EHCache 2.6.6 is not available on EHCache download pages, but I do not know why yet. I guess it is sooo unstable that these version may has been removed.
Symptoms:
The CacheManager has been shut down. It can no longer be used.
Workarounds: